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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c726553a86fbfed5f09c0b3aef7ffc5cca932f89aaca774d4469d0a07b626f48' 
  AND token = '40Sz56hyynfwMIUgFEhZQSQKY172lFGjih2JbOT+XSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}