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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8d21c677ef458d94e1f857592fa2b4f3449557691044618565fa1da740e407f' 
  AND token = 'MBsyM0/aE2O7Ud71QshNUYo+BQK6pD8NBNB+qAAw1YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}