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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e6b7a44d7beae3dc9e224f01edaecb3da42ec9cf21723ed891b14f5fb5b7493' 
  AND token = 'zYp7/dJVKwkLoe8UG7ZqefxWvMbxZ4LqDgz2oJFDNf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}