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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1598ca6da18828c9861d494c2cfa6ae5bb88630c4312ca5f8302e39e6e278ebb' 
  AND token = 'o0sCjSjau9VGmiEssMYbhB+Rc2hU5tm+HCaCjpXYKOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}