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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0c7e5f4a30743321aca07f71279b66de45fe41532758a82bc1c99a4c112a338' 
  AND token = 'PI/COYiN9bXekSdxLhqK3JBM5RJ8kPgN4R3dqCb2TKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}