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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5a601d09ad3883ab7211901d2a84b68b7f143b7f6318a6f3bce32029c05b17' 
  AND token = 'uMwrISAEfOgfrg66vN9OVggFXxOjOdXtRwPIya2/fSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}