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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c09e272ee4da094bf984f26592e350b964d96c9821a826e0cd9261394870c1e' 
  AND token = '+XOzAXzU52MSIefvv8sxzzy2CJiKWb05liO4k5I5bFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}