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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad621c63c5df0879426004214443f5326fb982bee26474f9450d94b84a0d9fed' 
  AND token = 'DVOUkFnAgqv9SxEaLiNyScgucU0L3GV6YcVQ9JP5tvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}