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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d4146106ac9e573e1498ac5d20e5069378ee3ac7072c7dd5f78c4e6253a30a' 
  AND token = 'A7dK8PEBXPMUAYNMvw0+jDg+27voeGtMIHUyKDhHEak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}