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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1f54548861edd389e5e42923abbdd0e26d7e48eb0379511dd44d5b102da2b0' 
  AND token = 'OzMdztKT1Ozr1IVMw3BuyFpHB3xN2Nc9mObCofW67S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}