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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '840ccb5ad590e5fd2a6541e9cd13731bac655fbe7216b8b8054bb23b495121c0' 
  AND token = 'MEP5IB7m42/e2ujbbgrauQE+BUdJwdilZO7HKmZIHG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}