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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cae8f2f8fed9d90f3100d6a0500a701becd9fe6a15db4d06b89bad5c9e79803a' 
  AND token = 'QiyVkMqywQnrGKUne1z/dLcVJ+VKY5fjDPxZYr0DcU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}