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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '393d43c5c33ddba9f5cd16a2ca4f8dd20aae4d2b6b0a6c2adc88004924498c2f' 
  AND token = 'DnvAgc1j1NHtsJgPyhjsRcXMjdXGqGBT7xOe0e9XpGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}