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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd50ca9dc16ae8bae391378a8050262837c8bb51ec719c616681b93b8722c0d' 
  AND token = 'C7P1Zh4k30sogGdzQ328txrIndGSwWaXxjpB/GzQdOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}