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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a0fa6448514119355a7f770a5dc5f1cdf3ddf707e7a3594d60b78fe457bc131' 
  AND token = '1Tv08xaMB2XfcLn+fP1yRvTMQFcILVB+IUjzHYiJGyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}