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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81da1fdcc65e85920700b4ccc337e4df3fd480ef1959d17dfac2efa056b20f3f' 
  AND token = 'oQVn8IgTKZiB053lRuWky9mwqNYvD02sn1G2Ljkl+5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}