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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '925136724ac8c4932d11c7d783a62a4880f8744a61aba98ec1cb8aa198d77060' 
  AND token = 't/GuPtNks3jYxX2PWHrNFgKpYPWMw3ly14cNM/h8aCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}