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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d74ddb48b4b02507e79778004bc9af2fcdd7b181fd5c82a2b8aacf66af849b1' 
  AND token = '7Bq6W0NN+w4SSufpgSEEdtiFKRoixmWkhAt7Wv5jbWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}