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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2609612478600c734df0debbbf2e8bab0e7fd9e17aa3c4ee379d8affe8337326' 
  AND token = 'K5E29Vp2E2670MMKaTWP8UnAGkW6rHMIoQ1EVzmZtAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}