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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a847d8f63a7ea8b1ad48351dac303ed592a5ce7cbdf70faf38bdce65975b21' 
  AND token = '1r5flkGC7EJY88gu9MAixetSSsFZyqIj5suTCVcRXLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}