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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd78b89293fe4f9f6adc66e5e0629f22d2afbcd010a596077e5071c1bf393211' 
  AND token = '1uM9hKUihsbzJhJMY8HyIZ/H/mG6Uzo5UYkdqPIt5aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}