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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c1066db669001a379f216a8cbcf0def9586ac6f781b76e4526eccbcc5bb70d' 
  AND token = 'UdBm6tdcxlqvKtFXZzAk8b1fnhTq88YsPQOYV3Rvy74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}