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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6223b81242569b07f5011c3c89f76726c90165c01dcf3b465f80eec564fa22' 
  AND token = '20NmQTEXkA9z0Lkbu8N1vV+OZJV2XEd6D9y3u+osLSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}