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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d346d2eff3c78ee277ad78a6aed8fc9898929b737b9770d80b5f5c8b692d379' 
  AND token = 'i+YBU6Asu/w948+JMvSfCriU11XB3vn6EeMKPzbdKP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}