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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70c97a81c2b1fa091c8d00d534c44f79f4b116e78945d20a39a421046cdd7844' 
  AND token = 'vNABBK6jL+F0Hf1AfaR3vacv+XTZyhGvW+7O+wwlVr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}