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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c292e98a48642e06a717da11b17e32310c248235e14b47e96ee5c498a538c5a' 
  AND token = 's+77EC7avHYanb7m1l6hr7rQiZfST24EeJeD4MWIJvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}