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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d5a380cf6d6a7b95379cf1a97c17e969255e74dd8c12321ac2d0b3b7234e39a' 
  AND token = 'dIQCYMX5kt9RSj643A8c6mEldTfPWBEGYYnxE4Cng/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}