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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d6a32e3c6366b35dcb208e5a28ca66e8b73d21116748bcd947912f0040921f8' 
  AND token = 'HPxRsot5BypXB/vg88Mm/sk4DdHE6laCPb6GAE6L+6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}