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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c018da9934fb628a9be6fdc51eb9d035368e0a21619e7e318cc8c3091e36336' 
  AND token = 'oqWQ4BFyoizb7yhovKjk0Qj8MH/Iy94n/I8Ux8H2xMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}