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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e23c3d276ff056fe3f0fdc035e95fc1164c6844f644e7148ff0013409da7c3' 
  AND token = '/EcAO2kK5ktNh9gG1EXU8GsUmO4MR0NWWIBFvG4WOSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}