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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a183199f08d8cb106ce998d15bd0299eb3bfc409f4b27f0b92c86867f97eff27' 
  AND token = 'Rz9+Hw31KlrddaiXPLgfe/IIfK6sN5pAYDm81DJX2fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}