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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d41b7023189e23ded54c59fdc5b4b7486cf60452b5cb0dfa1562c63874bfe8' 
  AND token = 'ANlZ+yF9Mm3chxrX5eFB1u0xO9Ik/F4TTYyc/qXAQlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}