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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a3fb2dffb3e11c678c6726de50ad8a9792f918c7023b5e91f7f01f1341bb59b' 
  AND token = '5PlAuXdF3t1ile3ZvqFT+BC0bdgwQ4Hz21Se/AvcctY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}