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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '868724cb70350565c4d35bd5cf852470b6c5b638b0bd414a8aafbb0dc454ae6e' 
  AND token = 'vIhDvxOsb9+lU+x9Xca4COR1ZkR4vIBW7lMv57KHaUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}