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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053e1f128b7c2f76c276a21697ecc53c5d78d6cea5c7474484df864f6373711a' 
  AND token = '6xKyMQHjMkxCnhsM0r4izSHpAXizT1DlMGJULGdFoDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}