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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f6d86501029b437925c8eae2295f83ed0b86b30468de814546f4fe0fbd5271' 
  AND token = 'ZGch4uowv86xybfjgEJydjif3WRA6mkwIVZMcC5C300=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}