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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41463e9a7bbbfa4398fe3cd4f0eb1a3c5bc64b22ce829f1c66564a9b71c850fd' 
  AND token = 'OA/ZYNqO0oz16COWXKhLIy2bTRiwf7KmXaQsoTnsR7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}