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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c02f08e77161249b53d91f73a432208bac4ffabd187f94f32cc4633afee52ec' 
  AND token = 'Zl1DUSInzWL+FU4uNmLStGInVHT5d7/FC0UjdlQwzl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}