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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cec9564a16a14ff764c4790380dea6a9fdea8a5f00d490e9bc38cb867dacf65' 
  AND token = 'lyz4n+DCkzk+HYf4HMev35sCv5OSbeBGMn0Gmc6aOVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}