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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d49d0882f0d778fa0e91087964eeb8df46b94baf48c596a61dfcee81b936c6f' 
  AND token = 'KTPZ0N4bG/EPT8I20XWwI5KV7Gs3yBQN3zBvVAC0j+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}