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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b19fe7d19a92f608d893dd3e4eb1678b22944dad02bd6428d28aaab48aa9e03' 
  AND token = 'PHBtflyVvu05w3KRwYqxZoiJgXTxkHWYH2/2p9lYew4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}