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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a465778119d421054f41c11d001a7f81d9521a69b80c6606114c277c883f8902' 
  AND token = 'Ij8Ak3UQRrrpjZxzgxPmIOl6bDl27oK5NE25BWvKcp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}