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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed26bcae10251aef794089fc4aa218da878aed2877a0164ee4b0522faf0a06bb' 
  AND token = '7iGWP5Ddt9hflvPAN7MhXtWFQ2Gmb5PQlGhRxfxAtKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}