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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d278bb634dad37975e739123b3e3e76d2899c37a9d7181557c1d4a92829997' 
  AND token = 'G5eNsN5b8C49uEz31Xgmza0qkNj+9piUoGgFoagzMxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}