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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7ace9d0ef48800d453814d6b04d16d20c8a8b9d106738c4cc8cdd4feb6e7d4' 
  AND token = 'vxjyOBShKlQU1JIeEAAkpdhtlpwFSp0ctB8+HNmxUsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}