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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e220c6b904e5072baba986b646dfec3637fe594c0794103fa932960fc13f1c92' 
  AND token = 'BIBn/NUmD1JT1AQLNhHxeGDvyX6vMAAypU2keygScuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}