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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c21fa34869a649965a70f7fca6a0e2e5936c1ad9740f9d3c054b3d0b3b7a874' 
  AND token = 'pn3ezINjILVnqgkx3XmrWN9o/zyONkMwWmtVsFCR/is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}