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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44aa273c2f757585d30570fb283ddc13ddc648e24630c7b77b83ffc771264c20' 
  AND token = 'i7PYoPH1Cwt2gLVpT/VEgV7IqmEyiSJZcCk56NCtAKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}