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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1fceee0830e81131075d982c917567c8b3d8381f8f2bb21bb3772da26369d6' 
  AND token = 'zpF/sKTCofgYgG2cXFXz0ulbdR8Mw7rQxm8gSw8msPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}