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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caa319b89a1a0a1580871298ce5b415c39ca14dfa969a4ddf7eaef59d54f9f10' 
  AND token = 'p3iy0yD6fpM+RASltFjH2W0VczeefybUuWOC6Z0Rxt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}